My Cholesterol is 221 HDL is 35.0 LDL 119.4 VLDL 75.6 Triglycerides 378 I was ove 250 pounds because of long term use of prednisone b/c of my lupus. I am currently at 185 pounds. I had my blood work done about a month and half ago. My doctor just put me on fish oil prescription to help with the cholesterol. I was 199 2 months ago so diet and exercising is working, but I was wondering how long roughly does fish oil and the diet and exercise take to lower the cholesterol. When should I have more blood work done. High cholesterol and heart problems run in my family I just want to do all that I can incase I need to take other medication if the diet and exercise is not enough. I am hoping the fish oil helps. I just don't know how long til I should weight to have my blood work done? Any information on weight, exercise, fish oil, cholesterol, or anything related would be greatly appreciated. Thanks.